The Dynamic Duo: Benefits of Combining Oral and Gut Probiotics

Dr Walter Tatch, Oral Maxillofacial Surgeon and Chief Medical Officer of StellaLife®

Keeping an eye on our oral and digestive health is crucial for sustaining a healthy lifestyle. Did you know that oral probiotics can have a big impact on your general wellbeing? They can! Scientists, medical professionals and dentists alike, are learning more about the advantages of taking probiotics for gut health. We’ll talk about the benefits of taking oral and intestinal probiotics together in this blog post, as well as how a probiotics kit that includes both can improve your life.

Benefits of Combining Oral and Intestinal Probiotics

  1. Enhanced Oral Health:
    • A healthy balance of beneficial bacteria in the mouth is encouraged by oral probiotics
    • Unique formulation of Pre and post-biotics to give both food and environment for good bacteria to flourish
    • Essential vitamins and minerals
    • Reduces and prevents plaque development
    • Reduces the risk of bad breath and gum disease
  2. Better Gut Health:
    • By preserving a healthy gut flora, gut probiotics assist the digestive system
    • Reduces irritable bowel syndrome (IBS) and other digestive problems’ symptoms
    • Encourages regular bowel movements and improved gut health
  3. Improved Immune System:
    • Mixing probiotics for the mouth and the intestines promotes a stronger immune system
    • Aids in preventing dangerous bacteria and viruses
    • May lower the risk of diseases and infections
  4. Improved Absorption of Nutrients:
    • Having a healthy gut microbiome promotes adequate nutrition absorption
    • By dissolving food particles, oral probiotics improve nutritional absorption
    • Supports general well-being and health
  5. Weight Control:
    • By enhancing metabolism, gut probiotics can assist in maintaining a healthy weight
    • By encouraging a balanced gut flora, one may lessen cravings for unhealthy foods
    • Better digestion brought on by taking oral probiotics can help prevent weight gain and boost weight loss efforts
  6. Lower Allergic Symptoms:
    • Probiotics taken orally and in the gut may reduce allergy symptoms by controlling the immune system
    • Helps maintain a healthy immune system that is better able to handle allergens
    • May lessen allergy-related inflammatory pain
  7. Improved Mental Health and Mood:
    • A balanced gut microbiota is associated with better mental and behavioral health
    • Probiotics taken orally and in the gut may help with the symptoms of anxiety and depression
    • Contributes to the general function and health of the brain


Combining oral and gut probiotics can significantly improve your wellbeing if you adopt a holistic approach to health. A probiotics kit with both can offer a practical and efficient method to get the advantages of both oral and intestinal probiotics in one container. You’re making a prudent investment in your health by introducing a probiotics kit such as this into your daily routine, which will result in a greater balance of healthy bacteria in your mouth and gut. Oral and gut probiotics are the ideal supplement to your wellness journey since it promotes better oral health, increased gut function, a stronger immune system, better nutrient absorption, weight management, reduced allergy symptoms, and a beneficial impact on mental health. 


Streptococcus salivarius M18 (BLIS M18®)

  • Cell- free supernatant of Streptococcus salivarius M18 impairs the pathogenic properties of Pseudomonas aeruginosa and Klebsiella pneumonia. Arch Microbiol. 2020 Dec;202(10):2825-2840.. SinemTunçer 1 2, SevinçKaraçam 3 4 
  • Streptococcus salivarius inhibits immune activation by periodontal disease pathogens. Reduction in Il-6 and 8. BMC Oral Health. 2021 May 7;21(1):245.Kyle MacDonald 1 2, Ryan M Chanyi 1 2, Jean M Macklaim 2 3, Peter A Cadieux 2 4, Gregor Reid 1 2, Jeremy P Burton 5 6 
  • Inhibitory effect of Streptococcus salivarius K12 and M18 on halitosis in vitro. Reduction of P ging and T. denticola. ClinExp Dent Res. 2020 Apr;6(2):207-214 Hyun-Jun Yoo 1, Su-Kyung Jwa 2, Da-Hui Kim 1, Yun-Jeong Ji 3 
  • Does Streptococcus Salivarius Strain M18 Assumption Make Black Stains Disappear in Children? Oral Health Prev Dent. 2020;18(1):161-164.Elena Bardellini, Francesca Amadori, EmanuelaGobbi, Anna Ferri, Giulio Conti, Alessandra 

Lactobacillus casei (Lc-11®)

  • Clin Infect Dis. 2006 Jun 15;42(12):1735-42.doi: 10.1086/504324. Epub 2006 May 4. Oral supplementation with Lactobacillus casei subspecies rhamnosus prevents enteric colonization by Candida species in preterm neonates: a randomized study. P Manzoni 1, M Mostert, M L Leonessa, C Priolo, D Farina, C Monetti, M A Latino, G Gomirato
  • Am J Dent. 2022 Apr;35(2):103-108. In vitro effect of an oral spray and mouthrinses on dual species cariogenic bacteria biofilm Parveez Ahamed Abdul 

Lactobacillus fermentum (SBS-1TM), Lactobacillus acidophilus (La-14®)

  • Microb Pathog. 2020 Feb 24;142:104063. doi: 10.1016/j.micpath.2020.104063.Online ahead of print. Antimicrobial activity of Lactobacillus fermentum TcUESC01 against Streptococcus mutans UA159

Lactobacillus gasseri (Lg-36TM)

  • Ann Microbiol. 2014;64(2):611-617.Lactobacillus salivarius and L. gasseri down-regulate Aggregatibacter actinomycetemcomitans exotoxins expression 
  • Lorenzo Nissen 1, Barbara Sgorbati1, Bruno Biavati1, Georgios N Belibasakis 2

Lactobacillus brevis (Lbr-35TM)

  • Anticancer Res. 2019 Apr;39(4):1935-1942.doi: 10.21873/anticanres.13303. Lactobacillus brevis CD2 for Prevention of Oral Mucositis in Patients With Head and Neck Tumors: A Multicentric Randomized Study Vitaliana DE Sanctis
  • J Indian Soc Periodontol. 2017 Jul-Aug;21(4):341-343. Long-term effect of Lactobacillus brevis CD2 (Inersan®) and/or doxycycline in aggressive periodontitis Mishal Piyush Shah 1, Sheela Kumar Gujjari 2, Veerendrakumar Siddhpur Chandrasekhar 2

Lactobacillus reuteri

  • J Clin Periodontol. 2013 Nov;40(11):1025-35. Clinical and microbiological effects of Lactobacillus reuteri probiotics in the treatment of chronic periodontitis: a randomized placebo-controlled study Wim Teughels 1, Andaç Durukan, Onur Ozcelik, Martine Pauwels, Marc Quirynen, Mehmet Cenk Haytac
  • J Oral Microbiol. 2017 Jan 18;9(1):1274582. Probiotic Lactobacillus reuteri has antifungal effects on oral Candida species in vitro. Mette Rose Jørgensen 1, Camilla Kragelund 1, Peter Østrup Jensen 2, Mette Kirstine Keller 1, Svante Twetman 1

Lactobacillus rhamnosus GG

  • BMC Microbiol. 2016 Jul 12;16(1):149. Interactions between Lactobacillus rhamnosus GG and oral micro-organisms in an in vitro biofilm model. Qingru Jiang 1, Iva Stamatova 2 3, Veera Kainulainen 4, Riitta Korpela 4, Jukka H Meurman 2

Lactobacillus paracasei (Lpc-37®) 

  • Probiotics Antimicrob Proteins. 2021 Apr;13(2):506-517.Probiotic Effects of Lactobacillus paracasei 28.4 to Inhibit Streptococcus mutans in a Gellan-Based Formulation. Janaína Araújo de Alvarenga 1, Patrícia Pimentel de Barros 2, Felipe de Camargo Ribeiro 1, Rodnei Dennis Rossoni 1, Maíra Terra Garcia 1, Marisol Dos Santos Velloso 1, Shashank Shukla 3, Beth Burgwyn Fuchs 4, Anita Shukla 3, Eleftherios Mylonakis 4, Juliana Campos Junqueira 1

Bifidobacterium bifidum, Bifidobacterium lactis

  • Clin Infect Dis. 2005 Jan 1;40(1):28-37.Microbiological effects of consuming a synbiotic containing Bifidobacterium bifidum, Bifidobacterium lactis, and oligofructose in elderly persons, determined by real-time polymerase chain reaction and counting of viable bacteria Sabine Bartosch 1, Emma J Woodmansey, Jacqueline C M Paterson, Marion E T McMurdo, George T Macfarlane